MICR   365. Infection and Immunity (Dental Hygiene). 2 Hours.

Semester course; 2 lecture hours. 2 credits. A study of infectious diseases and the immune system of humans with emphasis on the distribution properties and roles of pathogenic microorganisms and the varied responses of the host, with emphasis on oral pathologies. Principles of prevention, control and chemotherapy of infectious diseases are major components of the course.

MICR   501. Infection and Immunity (Pharmacy). 4 Hours.

Semester course; 4 lecture hours. 4 credits. Offered to pharmacy students in the first professional year. Others admitted with permission of instructor. A course on the fundamentals of microbiology and immunology with aspects on disease and treatment of interest to dentistry and pharmacy.

MICR   505. Immunobiology. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Background in cellular and molecular biology, and biochemistry is recommended. Nondegree-seeking students admitted with permission of instructor. A survey of immunobiology as a total host response to foreign agents, covering the nature of antigens and antibodies, antigen-antibody reactions, immunocompetent cells, allergic reactions, tumor immunology, transplantation immunology, immunological diseases and immunogenetics.

MICR   513. Infection and Immunity (Dentistry). 4 Hours.

Semester course; 4 lecture hours. 4 credits. Offered to dental students in the first professional year. Others admitted with permission of instructor. A course on the fundamentals of microbiology and immunology with aspects on disease and treatment of interest to dentistry and pharmacy.

MICR   515. Principles of Molecular Microbiology. 3 Hours.

Semester course; 3 lecture hours. 3 credits. A comprehensive course designed to provide the student with a thorough understanding of microbial physiology, genetics and diversity. Also covered are some basic concepts in microbial pathogenesis and in applied microbiology. The course focuses on structural and functional characteristics of micro-organisms; ecological and physiological diversity of microbes; growth and control of micro-organisms; genetics of bacteria and viruses; bacteria as agents of disease; and applications of microbiology.

MICR   605. Prokaryotic Molecular Genetics. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Prerequisites: BIOC   530, BIOC   531, BIOC   532 and BIOC   533; or BIOC   503 and BIOC   504; or permission of instructor; MICR   515 or equivalent recommended. A comprehensive introductory course examining the organization of the genetic material in bacteria and their viruses and the molecular mechanisms involved in its maintenance, replication, exchange and expression. Emphasis will be on experimental approaches integrating classical and modern methods of genetic analysis with biochemical studies of genetic regulatory mechanisms.

MICR   607. Techniques in Molecular Biology and Genetics. 2 Hours.

Semester course; 2 lecture hours. 2 credits. Prerequisites: BIOC   530, BIOC   531, BIOC   532 or BIOC   533; or BIOC   503 and BIOC   504 or equivalent; permission of instructor. Designed to give an overview of the techniques utilized in modern molecular biology. The principles underlying techniques such as plasmid and phage cloning, RNA and DNA analysis, PCR, DNA sequencing, mutagenesis, genomic mapping, heterologous gene expression, and production and analysis of recombinant protein and transgenic mouse technology will be discussed in detail by experts in the field.

MICR   608. Introduction to Microbiology and Immunology Research. 3 Hours.

Continuous courses; lectures and 4 laboratory hours. 3-3 credits. Prerequisite: Permission of instructor. Required of all first-year graduate students. Introduction to all active research programs in microbiology and immunology. Presentations of research programs by investigators and rotation of students through faculty laboratories to gain direct exposure to individual research projects.

MICR   609. Introduction to Microbiology and Immunology Research. 3 Hours.

Continuous courses; lectures and 4 laboratory hours. 3-3 credits. Prerequisite: Permission of instructor. Required of all first-year graduate students. Introduction to all active research programs in microbiology and immunology. Presentations of research programs by investigators and rotation of students through faculty laboratories to gain direct exposure to individual research projects.

MICR   616. Mechanisms of Viral and Parasite Pathogenesis. 3 Hours.

Semester course; 3 lecture hours. 3 credits. A comprehensive introduction to the basic principles of virology and human parasitology. Interactions of the infecting agents and hosts will be stressed at the molecular and cellular level.

MICR   618. Molecular Mechanisms of Bacterial Pathogenesis. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Prerequisites: undergraduate-level courses in microbiology or microbial physiology, immunology and molecular genetics. The goals of this comprehensive course are to explore in detail the virulence mechanisms of microbes and the response of the infected host. The focus will be on important bacterial pathogens.

MICR   653. Advanced Molecular Genetics: Bioinformatics. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Prerequisites: Cell/molecular biology or permission of instructor. An advanced course on contemporary bioinformatics. Topics covered include the principles and practice of DNA, RNA and protein sequence analysis, computational chemistry and molecular modeling, expression array analysis and pharmacogenomics. The course includes lectures, reading, computer lab, homework problem sets and projects. Crosslisted as: BNFO   653.

MICR   684. Molecular Biology of Cancer. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Prerequisites: BIOC   530, BIOC   531, BIOC   532 and BIOC   533; or BIOC   503; or permission of instructor. Advanced graduate-level course to provide theoretical background to graduate students interested in cancer research. Emphasis will be placed on experimental approach integrating classical and modern methods of genetic analysis with biochemical studies in genetic regulatory mechanisms. The course includes presentations by students and interactive discussion of the scientific literature in the area of oncogenesis.

MICR   686. Advanced Immunobiology. 3 Hours.

Semester course; 3 lecture hours. 3 credits. Open primarily to residents, medical students and graduate students with an immunology background such as MICR   505. Lectures, seminars, conferences on basic and clinical immunobiology and literature review on the topic, with more emphasis on methods in immunology research and exercising the ability to communicate the topic verbally. Topics have included tumor immunology, cell interactions in the immune response, genetics of the immune response, mechanisms of host-defense and membrane receptors in immunology and neoplasia.

MICR   690. Microbiology Research Seminar. 1 Hour.

Semester course; 1 lecture hour. 1 credit. Presentation and discussion of research reports and topics of current interest to the departmental seminar or special group seminars.

MICR   691. Special Topics in Microbiology. 1-4 Hours.

Semester course; 1-4 credits. Lectures, tutorial studies, and/or library assignments in selected areas of advanced study not available in other courses or as part of the research training.

MICR   692. Current Topics in Molecular Pathogenesis. 1 Hour.

Semester course; 1 lecture hour. 1 credit. Open to all graduate and certificate students. Presents a forum for the discussion of recent advances in the study of the molecular mechanisms of microbial pathogenesis. Consists of presentations by students, postdoctoral fellows and faculty followed by interactive discussions of the implications of presented work to the study of molecular pathogenesis.

MICR   693. Topics in Molecular Biology and Genetics. 1 Hour.

Semester course; 1 lecture hour. 1 credit. Open to all graduate students. Presents a forum for discussion of the scientific literature in the area of molecular biology and genetics, focusing on molecular mechanisms involved in regulation of gene expression and cell growth with examples from all three kingdoms of life. Consists of presentations by students and interactive discussions of the implications of presented work to the study of molecular biology.

MICR   694. Current Topics in Immunology. 1 Hour.

Semester course; 1 lecture hour. 1 credit. Open to all graduate students. Presents a forum for discussion of the scientific literature in the area of cellular and molecular immunology, focusing on mechanisms involved in the operation and regulation of the vertebrate immune system. Consists of presentations by students and interactive discussions of the implications of presented work to the study of immunology.

MICR   695. Special Topics in Microbiology. 1-4 Hours.

Semester course; 1-4 variable hours. 1-4 credits. Lectures, tutorial studies, library assignments in selected areas of advanced study or specialized laboratory procedures not available in other courses or as part of the research training. Graded as S/U/F.

MICR   697. Directed Research in Microbiology. 1-15 Hours.

Semester course; 1-15 credits. Research leading to the M.S. or Ph.D. degree and elective research projects for other students.